
Researchers at the Scripps Research Institute have created a vaccine that stops the high one gets from from heroin. Designed as a therapeutic option for those trying to break their addiction, the vaccine produces antibodies that stop heroin as well as other psychoactive compounds metabolized from heroin from reaching the brain to produce euphoric effects.
Previous efforts to create a clinically viable heroin vaccine have struggled because heroin is metabolized into multiple substances that each produce psychoactive effects. To overcome this problem the researchers, led by the study's principal investigator, Kim D. Janda, targeted not just the heroin itself, but also the chemical it quickly degrades into, 6-acetylmorphine (6AM), and morphine.